Breast Cancer Translational Research Laboratory, Institute J. Bordet

 

GROUP LEADER:                                                          

Christos SOTIRIOU, MD, PhD     

+32 2 541 3339

 

ADMINISTRATIVE ASSISTANTS: 

Jeanne LETOR / Dominique ROELS

Dominique.roels@bordet.be                                                                                                        

+32 2 541 3457

 

 

 

MEMBERS:

Collaborators Scientific:                                                              

Michail IGNATIADIS, MD, PhD                         

Luis TEIXEIRA, MD, PhD (visiting researcher)                                                      

                                                                                                                                                              

Postdoctoral Fellows:

Françoise ROTHE, PhD

Christine DESMEDT, PhD

Marion MAETENS, PhD

David VENET, PhD (bioinformatician) 

 

 

PhD Students:

Vinu JOSE

David Norman BROWN

Bastien NGUYEN

Floriane DUPONT

 

 

Technicians:

Ghizlane ROUAS

Samira MAJJAJ

Delphine VINCENT

Naïma KHEDDOUMI

Yacine BARECHE

 

 

 

PROJECTS:

 

1.     Identification of predictive biomarkers associated with prognosis and response to therapies in breast cancer for disease monitoring, early relapse detection and resistance to treatments assessment.

2.     Deciphering inter-, intra-tumor heterogeneity and tumor progression using high throughput technologies including next generation sequencing.

3.     Liquid biopsy as a tool to investigate and monitor metastatic breast cancer

4.     Phylogenetic reconstruction of metastatic dissemination and invasion and development of distant metastasis in breast cancer.

5.     Genomic and epigenetic alterations associated with breast cancer.

6.     Characterization of key molecular alterations in breast cancer tumorigenesis : Deciphering resistance to chemotherapy and identifying new treatment strategies.

7.     Impact of pregnancy on breast cancer biology and prognosis

8.     RNA editing in breast cancer