Cell Cycle Laboratory, ULB

 

GROUP LEADER:

Pierre P. ROGERPh.D

Pierre.Roger@ulb.ac.be

+ 32 2 555 4153

 

Group web page

                

ADMINISTRATIVE ASSISTANTS:

Geneviève  DALLE

gdalle(at)ulb.ac.be

+ 32 2 555 4133

Joëlle SENTE

jsente(at)ulb.ac.be

+ 32 2 555 4135

 

MEMBERS:

 

Postdoctoral Fellows:

Eric RASPÉ, Ph.D.

Katia COULONVAL, Ph.D.

Sabine PATERNOT, Ph.D.

Jaime PITA, Ph.D.

 

Technicians:  

Vincent VERCRUYSSSE

 

PhD Thesis:

Colleoni Bianca (2017) : Critical mechanisms of CDK4 activation, the key of cell cycle commitment and an essential target of oncogenic processes. Roles of p21 phosphorylations and identification of novel CDK4 activating kinases. (Adviser : P. Roger)

 

Project :

Using various molecular, cellular, proteomic and bioinformatic approaches, they are currently :

a) exploring the mechanisms of CDK4 regulation that determines the inactivation of the central oncosuppressor protein pRb and the cell cycle decision in normal and cancerous cells;

b) developing novel tools to predict whether cancer patients will benefit or not of treatments with the new CDK4 inhibitory drugs that are very successfully tested by several pharmaceutical companies.