Laboratory of Oncology and Experimental Surgery (L.O.C.E.), Institute J. Bordet

 

GROUP LEADER:                                                          

Ghanem-Elias GHANEM, PhD                                  

gghanem@ulb.ac.be                                                                                                                           

+ 32 2 541 3296    

 

ADMINISTRATIVE ASSISTANTS:

Christiane MEUNIER

Leila BERDOUZ (Data Manager)

loce@bordet.be

+32 2 541 3297

 

MEMBERS:

Collaborators Scientific:

François Salès, MD                               

Catherine Sibille, MD, PhD                                                                                                                 

                                                                                                                                                                

Postdoctoral Fellows:    

Fabrice JOURNE, PhD

Mohammad KRAYEM, PhD

Renato MORANDINI, PhD

Léna WIMANA, PhD

 

PhD Students:

Ahmad NAJEM

Murielle WIEDIG

 

Technicians:

Isabelle BORSU

Marie-Jeanne GEBSKI      

Philippe MERSCH

Marie-Lydie PILGRIMS

Zakia SENHAJI 

Sebahat YILDIRIM

 

 

Projects:

1.     MAPK pathway as a target for therapy in melanoma

2.     Evaluation and mechanism of action of novel anticancer targeted drugs: Dasatinib, a tyrosine kinase inhibitor in melanoma

3.     TYRP1 (tyrosinase-related protein 1) as prognosis marker and target for therapy - TYRP1 function and regulation by miRNA

4.     Kinome, gene expression and mutation profiling to predict response to new therapies in metastatic melanoma and to bring new insights in mechanism of resistance

5.     Establishment and characterisation of human melanoma cell lines

6.     Kinome and mutation profiling in melanoma